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Assessing the quality of randomized controlled trials: Enhanced urinalysis as a screening test for urinary tract infection. Indian Journal of Pediatrics.

The DOR is used as an overall measure of diagnostic accuracy. We used both weighted and unweighted models.

Simultaneous voiding cystourethrography and voiding urosonography. These items were therefore included as dichotomous variables. Using the DOR to investigate heterogeneity may thus miss relevant clinical associations.

Comparison of ultrasound examination and intravenous urography after a urinary tract infection. In general, the results of weighted analyses showed more intuitive associations. The primary objective of this study was to determine the extent to which variations in the quality of bqcterioscopico studies impact the results of a diagnostic meta-analysis and whether this differs with diagnostic test type.

A large diagnostic systematic review was required to enable the use of regression analysis to investigate the impact of components of quality upon results. Direct pooling of sensitivity and specificity using bivariate models in meta-analysis of studies of diagnostic accuracy. Usefulness of procalcitonin and C-reactive protein rapid tests for the management of children with urinary tract infection.


How does study quality affect the results of a diagnostic meta-analysis?

Annals of Emergency Medicine. Three items showed strong evidence of an association with the DOR in the weighted analysis. Journal of Clinical Pathology. A method comparison study to assess the reliability of urine collection pads as a means of obtaining urine specimens from non-toilet-trained children for microbiological examination.

Comparison of power Doppler ultrasonography with 99mTc-DMSA renal scintigraphy in the diagnosis of acute pyelonephritis. The use of an inappropriate spectrum of patients badterioscopico inadequate reporting of inclusion criteria were problematic for studies in this category.

Using the DOR to investigate heterogeneity means that we cannot assess whether the factors investigated are associated with paired measures of diagnostic accuracy, such as sensitivity and specificity, or positive and negative likelihood ratios. Polymorphonuclear elastase as a diagnostic marker of acute pyelonephritis in children. The value of ultrasound for diagnosing the uropathy in children with urinary-tract infections.

All studies included in this review were assessed using QUADAS, an evidence-based tool for the assessment of quality in systematic reviews of diagnostic accuracy studies. This was similar to the situation seen for studies on the localisation of infection.

Potential utility of MRI in the evaluation of children at risk of renal bacterioscipico. Canadian Exaemn Association Journal. Factors that lead to this pattern of change may have no effect on an overall measure such as the DOR.

However, for urinary leukocyte esterase, the unweighted analysis found strong evidence of an association between patient age and the DOR. The architecture of diagnostic research.


Tests involving dipstick or microscopy techniques were the only categories where enough studies were available to enable regression analysis. Urinary N-acetyl-beta-glucosaminidase and betamicroglobulin in the diagnosis of urinary tract infection in febrile infants. Only the evaluation of ultrasound for the localisation of infection provided bacterioscoopico data eaxmen enable the conduct of regression analysis 20 studies [ 48699799 —,,].

Early 99mTc dimercaptosuccinic acid DMSA scintigraphy in symptomatic first-time urinary tract infection. Outcomes research in radiologic imaging: Use of urinary gram stain for detection of urinary tract infection in infants.

How does study quality affect the results of a diagnostic meta-analysis?

By contrast, exwmen used to investigate confirmed UTI mainly utilised imaging technologies which are largely subjective in their interpretation, and where diagnostic thresholds are difficult to define.

Dipstick screening for urinary tract infection. The STARD initiative has provided clear guidance for the reporting of diagnostic accuracy studies [ 5 ]. Are these two methods comparable?

Color flow Doppler sonography in the diagnosis of vesicoureteric reflux. Using evaluations of diagnostic tests: For microscopy for pyuria and bacteriuria a variable on whether the sample was centrifuged was included, and for microscopy for bacteriuria a variable for Gram stain was included.

Can urine clarity exclude the diagnosis of urinary tract infection?

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