Holothoria atra, is a holothurian of order Aspidochirotes belonging to the family Description a Sea Cucumber Species Holothuria atra Jaeger, from. Native range | All suitable habitat | Point map | Year This map was computer-generated and has not yet been reviewed. Holothuria atra AquaMaps Data. Holothuria (Holothuria) atra Jaeger, AphiaID. (urn:lsid: :taxname). Classification. Biota; Animalia.

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The GC-MS analysis revealed the presence of 59 compounds. North Australian Sea Cucumbers L. Structure of neuritogenic active gangliosides from the sea cucumber Stichopus japonicas; pp. Oligosaccharide mapping of low molecular weight heparins: C15H24 24 2,poxy-5,8-hectadecadienol C17H30O2 Saponins the secondary metabolites which are triterpene glycosides present in sea cucumbers like H. Devaraj Isaac Dhinakaran, Email: After washing the column with same solvents, the sample 3 to 5 ml was poured and then eluted with methanol: It also showed the appearance of two carbon signals.

IC 50 values were calculated Percentage inhibition of novel compounds against all cell lines was calculated using the following formula: Similarly the inhibitory action of extracts were found against the HSV-1 and HSV-2 strains was analyzed by plaque reduction assay. Some of the bioactive compounds identified with their structures are given below. Sphingoid base composition of cerebrosides from sea cucumber Stichopus variegatus exhibited cytotoxicity against human colon cancer cell and induced apoptosis.


It favours reef flats where it is not fully exposed to the waves but the water is well aerated, and shallows beside slabs of rock from under which cool water wells out when the tide retreats. Spirostan and furostan steroid saponins, pregnane glycosides have a potential to be used as cancer therapies.

All authors read and approved the final manuscript. Retrieved from ” https: This article is published under license to BioMed Central Ltd. The cell inhibition hlothuria determined from the extract concentration ranged from 0. Holothuria atra emits a toxic red fluid when its skin is rubbed or damaged, which is a defense against predators.

Marine Species Identification Portal : Holothuria atra

In such places it is often found in pools above the low tide mark which are warmed by the sun during the day. It was found that H.

Associated Data Supplementary Materials Additional file 1: NMR analysis The active fractions obtained from column chromatography were analysed for Nuclear magnetic resonance spectroscopy NMR analysis. Holotguria carried out the studies on antitumor and antiviral activities using the H.

Holothuria atra

Trypan blue dye exclusion test Being an essential dye, Tryphan blue was used in estimating the number of viable cells present in a population. The antiviral activity was defined as the percentage of plaque inhibition as follows:. Sulfated polysaccharides from sea cucumbers such as the Cucumaria japonica, Holothuria impatiens are reported to exhibit antiviral activity.


Implications for selfoligomerization and haemolytic processes. Considering this as an evidence in the present study, attempts were made to find out the bioactive compounds from marine invertebrates such as the Holothuria.

The color is uniformly black and the body is often more or less completely covered by sand grains adhering to the skin.

Hillaside C a triterpene derived from sea cucumber Holothuria hilla inhibited the growth of human leukemia, breast and colon cancer cells in vitro in a dose and time-dependent manner by a mechanism that required induction of apoptosis and the concomitant reduction of the apoptosis-suppressing protein Bcl-effect Wu et al.

Fuscocineroside C bioactive compound obtained from sea cucumber Holothuria fuscocinerea a triterpene glycoside showed cytotoxic holothhria against human cancer cells Zhang et al.

They have been found in the body wall mucus Hisamatsu et al. Using MTT assay it could be inferred that H. The plaques were counted by visual examination and the percentage of plaque inhibition was calculated. Nat Rev Drug Discov. Holothuria atra Common name: Acknowledgments The authors are grateful and thankful to Dr.

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